Original Research Article
Year: 2020 | Month: October | Volume: 7 | Issue: 10 | Pages: 546-550
Susceptibility Pattern of Methicillin Resistant Staphylococcus Aureus (MRSA) Among All Clinical Isolates in a Tertiary Care Hospital in Eastern India
Kabita Choudhury1, Sk Md Imran Ali2, Sonia Deb3, Swagata Ganguly Bhattacharjee4
1Demonstrator, NRS Medical College & Hospital, 138, A.J.C Bose Road, Kolkata -14
2MSc Student, West Bengal State University, Kolkata.
3Senior resident, Calcutta School of Tropical Medicine, 108 Chittaranjan Avenue, College square, Kolkata-73.
4Professor and Head, NRS Medical College & Hospital, 138, A.J.C Bose Road, Kolkata -14
Corresponding Author: Swagata Ganguly Bhattacharjee
ABSTRACT
Introduction: Methicillin resistant Staphylococcus aureus (MRSA) from the late 1960s till date has emerged as a significant cause of morbidity and mortality and leading cause in both community and hospital acquired infections. This present study is an initiative to assess the burden of Methicillin resistant Staphylococcus aureus (MRSA) and to study their susceptibility pattern among all clinical isolates in this tertiary care hospital of eastern India, thus providing a national level initiative to highlight emerging trends of antimicrobial resistance among clinical isolates of Staphylococcus aureus.
Aims & Objective: Aim of the present study is-1. to know the prevalence of MRSA among Staphylococcus aureus isolates from all clinical specimens, 2. to study the susceptibility pattern of the MRSA isolates
Methodology: The present study was done retrospectively in the Department of Microbiology, Nil Ratan Sircar Medical College & Hospital, Kolkata, from January 2019 to January 2020 (13 months). A total of 859 isolates of Staphylococcus aureus, isolated from various clinical specimens were included in the study. A total of 859 isolates of Staphylococcus aureus, isolated from various clinical specimens were included in the study. Following identification of Staphylococcus aureus isolates antibiotic susceptibility was perform by Kirby Bauer disc diffusion technique using CLSI recommendations. Cefoxitin (30µg) was used for testing Methicillin resistance.
Results And Discussion: A total of 859 isolates of Staphylococcus aureus, out of which 403(46.9%) isolates were phenotypically Methicillin resistant. The prevalence of MRSA in our study is 46.9% which is an alarming figure.
Keywords: Staphylococcus aureus, MRSA, Cefoxitin.
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