IJRR

International Journal of Research and Review

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Original Research Article

Year: 2019 | Month: July | Volume: 6 | Issue: 7 | Pages: 318-323

Study of Prevalence of Hepatitis B and Hepatitis C in Hemophiliacs in a Tertiary Care Hospital in Northern India

Dr. Shazia Hamid1, Dr. Ritu2, Dr Shahbaz Khan3

1Asstt. Professor Deptt. Of Medicine GMC Jammu.
2Resident Deptt. Of Medicine GMC Jammu.
3Senior Resident Deptt. of Medicine GMC Jammu.

Corresponding Author: Dr Shahbaz Khan

ABSTRACT

Background: Hemophilia is an X-linked recessive bleeding disorder caused by a deficiency in coagulation factor VIII (hemophilia A) or factor IX (hemophilia B). Transfusion-transmitted infections (TTI) are serious complications at Hemophilia patients treated by factor VIII and IX concentrates. The cause of manifestation of these infections is on the fact that concentrating coagulation factors are prepared of plasma from thousand of blood donors that did not undergo viral inactivation.
Materials and methods: The present study was conducted at Hemophilic Centres of Govt. Medical College and Associated Hospitals Jammu. This is a cross sectional prevalence study and was conducted over a period of one year after approval from members of ethical committee.
Results: In the patients, 77 (86.52%) were HCV negative and 12 (13.48%) were HCV positive. In the age group less than 18 years, all the 37 patients (100.00%) were HCV negative. A significant association was seen between age category and prevalence of HCV. (P<0.05)

Key words: Hepatitis B and Hepatitis C , Transfusion, Bleeding , Joints.

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