Case Report
Year: 2019 | Month: June | Volume: 6 | Issue: 6 | Pages: 215-217
Urticaria due to Ceftriaxone: A Case Report
Vageeshwari Devuni
CMR College of Pharmacy, Kandlakoya, Medchal Road, Hyderabad.ABSTRACT
Cephalosporin are one of the most commonly prescribed antibiotics along with penicillin’s, because of their broad spectrum of activity. As the therapeutic use of cephalosporin are increasing, reports of Hypersensitivity reactions are also on the rise. Ceftriaxone, a cephalosporin is used for variety of infections. The drug is known to be associated with rare and mild side effects such as Urticaria, skin rash, diarrhea, vomiting, transient neutropenia and hemolysis. Antibiotics are the most common causes of drug-induced urticaria, of which cephalosporins were the most common causative drugs. Safe way of diagnosing Cephalosporin induced specific gamma interferon, interleukin (IL)-5 and IL-10 release from peripheral blood mononuclear cells. The allergic manifestations are due to breakdown compound formed during drug metabolism.
Key words: Ceftriaxone, cephalosporin, Antibiotics, allergy, Urticaria, drug metabolism, diagnosis.
[PDF Full Text]