Original Research Article
Year: 2016 | Month: February | Volume: 3 | Issue: 2 | Pages: 11-17
A Study to Determine the Normative Data for Cord Blood Free Thyroxine and Thyroid Stimulating Hormone in Indian Babies
Avanish Kumar Yadav1, M.M Gupta2, Varun Kumar Singh1
1Medical Officer, Department of Paediatrics, ESI PGIMSR, Basaidarapur, New Delhi.
2Senior Consultant, Department of Pediatrics, Tirathram Shah Hospital, New Delhi.
Corresponding Author: Varun Kumar Singh
ABSTRACT
A study was conducted to determine the normative data for free thyroxine and thyroid stimulating hormone in cord blood. It was a prospective observational study with total of 1000 samples from umbilical cord were collected in a sterile container and free thyroxine(FT4) and thyroid stimulating hormone(TSH) estimation was done . The norms for TSH and FT4 were determined by calculating the descriptive statistics of TSH and FT4 in terms of minimum, maximum range, mean and S.D norms and standard error of mean. The percentiles were calculated as 1st, 3rd, 10th, 25th, 50th, 70th, 90th, 95th, 97th and 99th percentiles for deriving the norms for TSH and FT4. The level of statistical significance was taken as p≤0.05. The data was analyzed by using SPSS statistical software version 16.0.
Key words: Newborn, cord blood, FT4, TSH, newborn screening, normative data.